The Gene Box
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Welcome to the gene box. Here we unbox your curiosity about genome mystique and make it work for your advantage. Connect with us to explore possibilities.

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Technical FAQs

What is the current state of genetics technology and what’s the future?

Genetics technology is a relatively young field and rapidly evolving. In the near future, it’s inevitable that most individuals will, in one way or another, experience some level of genetic assessment. Currently, most genetic assessments are based on genotyping, which selectively looks at certain portions of the individual’s genes. In the future, the entire genetic code would be read in a matter of hours for an affordable price.

Will this assessment program be helpful for children?

Yes. Genes manifest at inception and do not change for life, though their expression can be modulated through the person’s environment (Diet, lifestyle and activity). Learning about one’s predispositions and genetic preferences to maximize health benefits will significantly improve the quality of life. From this perspective, since children have a better head start, getting a genetic assessment as early as possible will result in a significantly better quality of life for the child.

How do you work out my Genetic Risk score?

Genetic Risk can be defined as your chance of developing a particular health condition that tells you how (genetically) susceptible you are to that condition. Genetic risk for a condition can be evaluated and quantified using certain statistical entities like odds ratio (OR), relative risk (RR), absolute risk (AR) etc.

What does the The Gene Box test tell me about my general health?

The Gene Box tests are not designed to be used for general health or medical purposes, they are strictly focused on the role our genes play four our sporting or diet profiles.

How does one understand and interpret genetic results?

Genetics is about likelihood. Like a weather forecast which conveys that the probability of raining is 60%, , suggests that it most likely will rain, though it can’t be ignored that there is a 40% chance that it may not rain. However, not all genetics are like that. In certain genetic conditions called monogenic conditions, the likelihood is 100%. In certain others it varies all over the place between 99% to 1%. Scientists often combine the likelihood of multiple genes to increase the certainty of likelihood for a certain event. The proper way to interpret genetic likelihood is to become aware of your likelihood of various things, then verify through other pieces of information, if you can, and act on the side of caution. For example, if genetic tests reveal that certain individuals have a higher likelihood of diabetes, he/she should look for family history of diabetes and also monitor their blood glucose periodically. They should also take preventive action with regards to Diabetes. Not all conditions are easy to spot through family history like Diabetes; this is where genetic testing on a wide range of parameters such as nutri-genomic profile, fitness profile and profile of other health conditions is highly helpful. In summary, genetic testing is most useful to individuals who are knowledgeable, who are curious about themselves, who are proactive about their health and who know how to understand and use this information in the correct way.

What is genetic assessment?

Genetic assessment is the process of learning about an individual’s genes. This knowledge can then be used to improve your health outcome by adopting a proactive approach to your health. Genetic assessment can reveal a wealth of information about what kind of nutrition, fitness and lifestyle is uniquely suited to you, and is likely to have the best health impact on your body.

What are the conditions for which you calculate the predisposition?

We provide information on eight preventable lifestyle conditions, which are globally common and research suggests are avoidable through lifestyle, exercise and nutritional modifications.

Do you calculate the risk of getting cancer?

The Gene Box test focuses only on common and preventable lifestyle related conditions where nutritional and physical activity has been shown to make a significant difference in health outcomes. We inform the individual on the specifics of what nutrition and activity will uniquely suit their genetic type, so as to prevent lifestyle related conditions before the appearance of any symptoms and to achieve a superior quality of life.

Will my report be the same as my son‘s or father’s?

Every individual receives DNA from the father and mother in equal proportions. So no two individuals will be alike, except for identical twins. So your DNA will be different from your father’s and your son’s; though it is likely that there will be common elements among the three of you.

What are preventable conditions? How does your service help in preventing them?

A disease is associated with the manner in which a person or a group of people live. Lifestyle diseases include atherosclerosis, heart disease, and stroke; obesity and type 2 diabetes; and diseases associated with smoking and alcohol and drug abuse. In recent times there has been a significant increase in the prevalence of lifestyle conditions globally, which are preventable by adhering to proper nutrition and induction of physical activity into the daily routine. However, given that we are all genetically different from each other, the same nutrition, physical activity and lifestyle may not be maximally beneficial to each of us. Currently, a one-size-fits-all approach is what is available to people by way of generic nutritional and fitness advice.

Is this test approved?

Yes, the saliva testing is done in a state of the art laboratory certified by National Accreditation Board for Testing and Calibration Laboratories (NABL), which is an autonomous body under the aegis of Department of Science & Technology, Government of India, and is registered under the Societies Act.

I have a family history of diabetes, I would like my children to be free of diabetes, and how can your service help?

Type 2 diabetes has a stronger link to family history and lineage than type 1, although it too depends on environmental factors. Yet two factors are important in both. That is, you inherit a predisposition to the disease and then something in your environment triggers it. By studying identical twins, researchers from Lund University in Sweden have identified mechanisms that could be behind the development of type 2 diabetes. This may explain cases where one identical twin develops type 2 diabetes while the other remains healthy. Lifestyle also influences the development of type 2 diabetes. If you have a family history of type 2 diabetes, it may be difficult to figure out whether your diabetes is due to lifestyle factors or genetic susceptibility. Most likely it is due to both. However, don’t lose heart. The Gene Box genetic assessment can analyse your children’s genes for diabetes and many other preventable lifestyle diseases and will tailor a nutri-genetic diet pattern and exercise, which best suits his/her genes. Hence by understanding the genetic profile of your kid and by modifying the lifestyle conditions we can ensure you that your children can be free of diabetes.